Factor V G1691A (Leiden) is a major etiological factor in Egyptian Budd-Chiari syndrome patients
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چکیده
منابع مشابه
Factor V G1691A (Leiden) is a major etiological factor in Egyptian Budd-Chiari syndrome patients.
OBJECTIVE Budd-Chiari syndrome is a multifactorial disease in which several prothrombotic disorders may predispose patients to the development of thrombosis at this uncommon location (hepatic veins). The aim of this study was to determine the prevalence and characteristics of inherited thrombophilia in Egyptian Budd-Chiari syndrome patients. METHODS The study included 47 Budd-Chiari syndrome ...
متن کاملA Young Boy with Budd Chiari Syndrome Secondary Heterozygous to Factor V Leiden – a Case Report
Budd Chiari syndrome (BCS) is a rare condition with exact incidence not known. It results from obstruction to the venous outflow of liver anywhere from the hepatic veins till the terminal inferior vena cava. Most cases are idiopathic; commonest cause being hypercoagulable state. Other causes include hepatic or metastatic malignancies, infections, inflammatory bowel disease, Behcet syndrome, asp...
متن کاملFrequency of factor V Leiden (G1691A) and prothrombin (G20210A) polymorphisms in Population of Kerman Province, Iran
Background & Aims:Thromboembolism is an acute cardiovascular disease that ranges from clinically unimportant to massive embolism. Both acquired and hereditary risk factors contribute to the disease. We aimed to determine the prevalence of two hereditary predisposing factor of the disease, prothrombin G20210A and factor V Leiden (G1691A) polymorphisms, in Kerman population.<br /...
متن کاملRisk of Budd-Chiari Syndrome Associated with Factor V Leiden and G20210A Prothrombin Mutation: A Meta-Analysis
BACKGROUND Various studies have demonstrated that factor V Leiden (FVL) and G20210A prothrombin mutation contribute to the risk of Budd-Chiari syndrome (BCS), while other studies provided conflicting findings. In order to derive more precise estimations of the relationships, a meta-analysis was performed. METHODS Eligible articles were identified through search of databases including Pubmed, ...
متن کاملImpaired fibrinolysis as a risk factor for Budd-Chiari syndrome.
In Budd-Chiari syndrome (BCS), thrombosis develops in the hepatic veins or inferior vena cava. To study the relationship between hypofibrinolysis and BCS, we measured plasma levels of fibrinolysis proteins in 101 BCS patients and 101 healthy controls and performed a plasma-based clot lysis assay. In BCS patients, plasminogen activator inhibitor 1 (PAI-1) levels were significantly higher than in...
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ژورنال
عنوان ژورنال: Turkish Journal of Hematology
سال: 2011
ISSN: 1300-7777,1308-5263
DOI: 10.5152/tjh.2011.84